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Reagents containing reactive end groups that respond to the presence of specific functional groups by forming bonds between polymer chains. Ideal for various applications including conjugation reactions, biomolecule labeling, and molecular purification.
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A synthetic glucocorticoid; inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 UG/animal) and by oxazolone in mice (ED50 = 0.8 UG/animal); has anti-inflammatory effects on croton oil-induced EAr edema in rats (ED50s = 10 UG/ml and 0.5 UG/ear) and mice (ED50s = 1.2 and <0.32 UG/ear after 6 and 24 hours of treatment, respectively)
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Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate)) is a water-soluble, homobifunctional, amine-reactive crosslinker used in biochemical research to covalently link proximal amine-containing residues and probe protein-protein or protein-peptide interactions. It is commonly used to map spatial relationships within protein complexes and to stabilize transient interactions for analysis.
Water-soluble crosslinker suitable for aqueous reactions.
Homobifunctional and targets primary amines.
Enables mapping of spatial proximity in protein complexes.
Supplied at research-scale quantity for laboratory use.
Typical purity approximately 90% as supplied.
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Formula: C23H18N2O5, Purity: 97%, MW: 402.4, DBCO-NHS Ester is an amine-reactive compound and can be used to modify an amine-containing molecule in organic solvents (limited solubility in aqueous media). It reacts with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. The low mass weight will add minimal spacer to modified molecules.
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Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt is a water-soluble, heterobifunctional cross-linker used to couple primary amines to sulfhydryl groups in proteins and peptides. It is designed for aqueous bioconjugation and chemical modification workflows where selective amine-to-thiol linking is required.
Water soluble heterobifunctional cross-linker suitable for aqueous reactions.
Selective amine-to-thiol coupling for targeted bioconjugation.
High reported purity for reliable reaction performance.
Soluble in DMSO at approximately 50 mg/mL for stock preparation.
Available in small pack sizes for research and development use.
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A selective κ1-opioid receptor partial agonist (Ki = 32.6); inhibits forskolin-stimulated cAMP production (EC50 = 4.7 nM); antinociceptive effects in mice at 13 UG, i.c.v.
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A secondary metabolite produced by some species of lichen that binds FAS-II enzymes to produce antibacterial and antiplasmodial effects; inhibits PfFabZ and PfFabI (IC50 = 10.7 and 36.1 µM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC50 = 77.3 µM)
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A lichen metabolite with diverse biological activities; active against various bacteria (MICs = 4-16 μg/ml); prevents UVB-induced apoptosis, cytotoxicity, and cytoskeletal modifications in HaCaT human keratinocytes from 25-800 μM; increases scratch wound healing of HaCaT cells; reduces hydrogen peroxide-induced production of ROS and cytotoxicity in HUVECs at 15 μM
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An ester of a naturally occurring phenolic compound that demonstrates antihyperglycemic and antidiabetic activity as well as induces anti-inflammatory and antinociceptive effects
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